Sarcoma Cancer is a rare disease, often misdiagnosed, often afflicting children and young adults.
The Karen Wyckoff Sarcoma Foundation is dedicated to Sarcoma Cancer research, support and education...and the fight to find a cure.

Welcome to Rein in Sarcoma

Though Sarcomas are rare, you are not alone in your battle against the disease. The Karen Wyckoff Rein in Sarcoma Foundation provides news, resources, and a way to connect to others with the disease. Since our inception in 2001, Rein In Sarcoma has had the opportunity to serve many individuals who, like you, have waged a personal war against this disease.

To learn more our mission, click on our video below.

For more background information about RIS, click here.

We thank you for the privilege of assisting you on your personal sarcoma journey.

  • Our Mission
  • Karen's Story
  • Contact Us
  • Patient and Family Support Programs
  • Coping with Cancer
  • Sarcoma Survivor Stories
  • Understanding Sarcoma Cancers
  • Local and National Resources
  • Sarcoma Patient Starter Notebook
  • For newly Diagnosed Sarcoma Patients
  • Understanding Sarcoma Cancers
  • Lumps & Bumps
  • Red Flags of Sarcoma Cancer
  • Educating the public and medical profession about the warning signs of sarcoma Cancers


  • Why support to Rein in Sarcoma?
  • Ways to Give
  • Named Tribute and Memorial Funds
  • Plan your own Fundraiser to Benefit Rein in Sarcoma

"Riding with a Purpose" - The Muds Dog Ride Again in February!

MUd Dogs RideThe 2014 annual Mud Dog Ride for RIS will coincide with the Minnesota United Snowmobilers Association 32nd annual Winter Rendezvous, February 6-9 at the Shooting Star Casino Hotel & Event Center in Mahnomen, MN in memory of snowmobile rider, Eric SkogmanThis year an anonymous donor is issuing a $1,500 Mud Dog Challenge Grant!  This donor has committed to match all new 2014 Mud Dog paid pledges  through Saturday, February 9th or when the challenge is met. Read more...

Natalie Wolf: Student, Sarcoma Survivor and Reseacrher to Find a Cure

David Largaespada and Natlaie Wolf at Recent RIS EventWorking with Dr. David Largaespada to cure Sarcoma

Three years ago, eighteen year old Natalie Wolf discovered a lump on her side, which her doctor said was benign. She didn’t like the looks of it so she insisted it be removed. The day before she moved into the dorms at the University of Minnesota to begin her freshman year, she received a call saying that the mass was found to be cancer. Read more...

Volunteer-Special Event Volunteer Opportunities

Rein in Sarcoma 15th Annual Party in the Park 

Monday, July 27, 2015

Como Park, East Picnic Pavilion, Visitor Center and Visitor Center Grounds, St. Paul, MN. Over 50 positions and 250 volunteer opportunities are listed below.  Sign up for a particular position and shift or just let us know to assign you wherever you are most needed. Questions? Contact Nancy Hendrickson, our Party in the Park Volunteer manager by email or call 651-214-5821

2013 Party in the Park- A Huge Success!

2013 Party in the ParkOur 13th annual "Party in the Park" was a magical evening of great music, entertainment and family fun.  Rein in Sarcoma 2013 featured unlimited carousel rides, continuous entertainment, a large and unique Silent Auction and children’s activities. Read more... 

Introducing the KWRIS Sarcoma Scholars for 2013-2014

SunFllower-Red Flags

For the past four years the Foundation has awarded scholarships to current medical students at the University of Minnesota to educate them about sarcoma cancers and to also encourage their interest in the field of oncology and research.  During their term of service, Sarcoma Scholars attend the Thursday morning radiation/oncology conference as their schedule allows.  Read more...